This inventor holds 2 USPTO granted patents and 1 EPO patent. Top assignees: Behring Diagnostics Gmbh, Dade Behring Marburg Gmbh. Active years: 1998-2001.
Company Filing History:
Years Active: 1998-2001
Title: Frank Berthold Breitling: Innovator in Human Antibody Libraries
Introduction
Frank Berthold Breitling is a notable inventor based in Wiesloch, Germany. He has made significant contributions to the field of biotechnology, particularly in the development of human antibody libraries. With a total of 2 patents, his work has advanced the understanding and application of antibodies in various medical and research settings.
Latest Patents
Breitling's latest patents include innovative methods for the preparation and use of gene banks of human antibodies. One of his inventions focuses on the preparation and use of gene banks of human antibodies, which involves translating mRNA from human B-lymphocytes into cDNA. This process utilizes oligo-dT primers and polymerase chain reaction (PCR) to amplify antibody-specific cDNA, ultimately creating a human-antibody library for in vitro screening of selected antigens. Another patent pertains to the preparation and use of gene banks of synthetic human antibodies. This invention involves forming hypervariable regions of antibody cDNA using a framework in a suitable vector, allowing for the creation of a synthetic human antibody library for screening with selected antigens.
Career Highlights
Throughout his career, Frank Berthold Breitling has worked with prominent companies in the biotechnology sector. Notable among these are Behring Diagnostics GmbH and Dade Behring Marburg GmbH. His work in these organizations has contributed to advancements in diagnostic and therapeutic applications of antibodies.
Collaborations
Breitling has collaborated with several professionals in his field, including Melvyn Little and Thomas Seehaus. These collaborations have further enriched his research and development efforts in the area of human antibodies.
Conclusion
Frank Berthold Breitling's innovative work in the field of human antibody libraries has made a significant impact on biotechnology. His patents reflect a deep understanding of antibody technology and its applications in research and medicine.