Franco Basile

Title: Innovations of Franco Basile in Protein Denaturation Monitoring

Introduction

Franco Basile is an accomplished inventor based in Fort Collins, CO (US). He has made significant contributions to the field of protein denaturation monitoring, holding a total of 5 patents. His innovative techniques have the potential to advance research in biological sciences and medical applications.

Latest Patents

One of Franco Basile's latest patents is a non-intrusive laser-based technique for monitoring and controlling protein denaturation on surfaces. This method involves using a low power laser, specifically a 5 mW, 362 nm diode laser, directed through a biological sample to a photodetector. The sample is heated by radiant heaters to temperatures between 220° C. and 250° C. over a period of 10 to 60 seconds. Throughout this treatment, the baseline transmissivity of the sample is continuously monitored via the signal voltage detected at the photodetector. When an increase in relative transmissivity is detected, the heating treatment is concluded, allowing for the biological sample to be removed for in situ protein identification as part of an imaging MALDI-MS measurement.

Career Highlights

Franco Basile has worked with notable institutions such as the University of Wyoming's Office of Research & Economic Development and the Wyoming Research Products Center. His work in these organizations has contributed to the advancement of research and innovation in the field.

Collaborations

Franco has collaborated with esteemed colleagues, including Shaofeng Zhang and Erica Belmont. These partnerships have fostered a collaborative environment that enhances the quality and impact of their research.

Conclusion

Franco Basile's innovative work in protein denaturation monitoring exemplifies the intersection of technology and biological research. His contributions are paving the way for advancements in understanding protein behavior, which can have significant implications in various scientific fields.