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For the Inventor, By the Inventor

Rome, Italy

Francesco De Angelis

USPTO Granted Patents = 17


Average Co-Inventor Count = 3.9

ph-index = 5

Forward Citations = 125(Granted Patents)


Location History:

  • 00136 Rome, IT (1999)
  • Rome, IT (1995 - 2010)
  • Genoa, IT (2023)

Company Filing History:

goldMedal15 out of 343 
 
Sigma-Tau Industrie Farmaceutiche Riunite S.p.a.
 patents
silverMedal2 out of 832,912 
Other
 patents

Years Active: 1995-2023

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17 patents (USPTO):Explore Patents
1. 11624744 - Method and device for recording intracellular action potential in electrogenic cells (2023-04-11),
2. RE41226 - Compounds having reversible inhibiting activity of carnitine palmitoyl-transferase (2010-04-12),
3. RE40861 - Compounds having reversible inhibiting activity of carnitine palmitoyl-transferase (2009-07-20),
4. 6822115 - Synthesis of (R) and (S)-aminocarnitine, (R) and (S)-4-phosphonium-3-amino-butanoate, (R) and (S) 3,4-diaminobutanoic acid, and their derivatives starting from D- and L-aspartic acid (2004-11-23),
5. 6528684 - Synthesis of (R) and (S) -aminocarnitine and their derivatives starting from D- and L-aspartic acid (2003-03-04),
6. 6444701 - Compounds having reversible inhibiting activity of carnitine palmitoyl-transferase (2002-09-03),
7. 6420599 - Chemical process for the stereoselective synthesis of R-(-)-carnitine (2002-07-16),
8. 6369073 - Compounds having reversible inhibiting activity of carnitine palmitoyl-transferase (2002-04-09),
9. 6316667 - Process for the preparation of R-(-)-carnitine (2001-11-13),
10. 6127552 - Process for producing (R)-3-hydroxy-4-butyrolactone useful for preparing (2000-10-03),
11. 5925369 - Bis alkanoyl esters of carnitine having bactericidal, fungicidal and (1999-07-20),
12. 5714619 - Process for the preparation of (S)-.beta.-hydroxy-.gamma.-butyrolactone (1998-02-03),
13. 5599978 - Process for manufacturing L-(-)-carnitine from a waste product having (1997-02-04),
14. 5532410 - Process for manufacturing L(-)-carnitine from a waste product having (1996-07-02),
15. 5532409 - Process for producing R-aminocarnitine and S-aminocarnitine (1996-07-02),

Title: Francesco De Angelis: Innovator in Electrophysiology

Introduction

Francesco De Angelis is a prominent inventor based in Rome, Italy, known for his significant contributions to the field of electrophysiology. With a total of 17 patents to his name, he has made remarkable advancements in the methods and devices used for recording intracellular action potentials in electrogenic cells.

Latest Patents

One of his latest patents is a method and device for recording intracellular action potentials in electrogenic cells. This innovative approach involves positioning a sample containing the cells on a multi-electrode array and utilizing laser pulses to perform localized breakdown of the cell membranes. The technology focuses on enhancing the electric field produced by the laser, allowing for precise recording of intracellular action potentials. Another notable patent involves compounds that exhibit reversible inhibiting activity of carnitine palmitoyl-transferase, showcasing his diverse research interests and expertise.

Career Highlights

Throughout his career, Francesco De Angelis has worked with Sigma-tau Industrie Farmaceutiche Riunite S.p.a., where he has contributed to various projects that bridge the gap between research and practical applications in the pharmaceutical industry. His work has been instrumental in advancing the understanding of cellular mechanisms and their implications for health and disease.

Collaborations

Francesco has collaborated with notable colleagues such as Maria Ornella Tinti and Fabio Giannessi, further enriching his research endeavors and expanding the impact of his innovations.

Conclusion

Francesco De Angelis stands out as a leading inventor in the field of electrophysiology, with a strong portfolio of patents that reflect his dedication to advancing scientific knowledge and technology. His contributions continue to influence the landscape of biomedical research and applications.

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