Company Filing History:
Years Active: 2005-2008
Title: Francesca Maria Pisani: Innovator in DNA Polymerase Technology
Introduction
Francesca Maria Pisani is a distinguished inventor based in Rome, Italy. She has made significant contributions to the field of biotechnology, particularly in the development of DNA polymerases. With a total of 2 patents, her work has advanced the capabilities of polymerase chain reaction (PCR) technology.
Latest Patents
Francesca's latest patents focus on mutant B-type DNA polymerases that exhibit improved performance in PCR. The first patent describes thermostable mutants of B-type DNA polymerases that contain a Y-GG/A amino acid motif between the N-terminal 3'-5' exonuclease domain and the C-terminal polymerase domain. In this invention, the tyrosine of the Y-GG/A amino acid motif is mutated, resulting in mutant DNA polymerases that are particularly suitable for PCR applications. This innovation enhances the efficiency and reliability of PCR, which is crucial for various genetic analyses.
Career Highlights
Francesca is currently employed at Roche Diagnostics GmbH, where she continues to push the boundaries of DNA technology. Her work at Roche has allowed her to collaborate with leading experts in the field, further enhancing her contributions to biotechnology.
Collaborations
Some of her notable coworkers include Harald Sobek and Bruno Frey. Their collaborative efforts have played a vital role in the development of innovative solutions in DNA polymerase technology.
Conclusion
Francesca Maria Pisani's work exemplifies the impact of innovation in biotechnology. Her patents and contributions to DNA polymerase technology are paving the way for advancements in genetic research and diagnostics.