The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 19, 2005

Filed:

Mar. 09, 2001
Applicants:

Harald Sobek, Penzberg, DE;

Bruno Frey, Penzberg, DE;

Garabed Antranikian, Seevetal-Hittfeld, DE;

Kristina Boehike, Berlin, DE;

Francesca Maria Pisani, Rome, IT;

Mosè Rossi, Naples, IT;

Inventors:

Harald Sobek, Penzberg, DE;

Bruno Frey, Penzberg, DE;

Garabed Antranikian, Seevetal-Hittfeld, DE;

Kristina Boehike, Berlin, DE;

Francesca Maria Pisani, Rome, IT;

Mosè Rossi, Naples, IT;

Assignee:

Roche Diagnostics GmbH, Mannheim, DE;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12P019/34 ; C12P021/06 ; C12N009/12 ; C07H021/02 ; C07H021/04 ;
U.S. Cl.
CPC ...
Abstract

The present invention relates to thermostable mutants of B-type DNA polymerases comprising a Y-GG/A amino acid motif between the N-terminal 3'-5′-exonuclease domain and the C-terminal polymerase domain whereas the tyrosine of the Y-GG/A amino acid motif is mutated and whereas these mutant DNA polymerases are suitable for PCR.


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