Frances Leslie

Title: Innovations by Frances Leslie in Nicotinic Acetylcholine Receptor Research

Introduction

Frances Leslie, an accomplished inventor based in Irvine, CA, has made significant contributions to the field of biochemistry. With a focus on the nicotinic acetylcholine receptor, her work aids in understanding various diseases and conditions linked to receptor dysfunction.

Latest Patents

Frances Leslie holds a patent for "Labeled ALPHA4BETA2 ligands and methods therefor." This innovative patent encompasses compositions and methods aimed at binding to the α4β2 nicotinic acetylcholine receptor in both in vitro and in vivo settings with high selectivity. The compounds described in her patent can be utilized for PET and SPECT analysis, which enhances imaging techniques in medical diagnostics. Additionally, these compounds can function as antagonists, partial agonists, or agonists in treating diseases connected to α4β2 dysfunction.

Career Highlights

Frances Leslie has made substantial strides in her career while working at the University of California. Her research has not only led to the development of groundbreaking technologies but has also positioned her as a key figure within the academic and scientific communities.

Collaborations

Throughout her career, Frances has collaborated with notable coworkers such as Jogeshwar Mukherjee and Ramaiah Pichika. These partnerships have been instrumental in advancing their common research goals and fostering innovation in their fields.

Conclusion

Frances Leslie’s dedication to her work has led to remarkable advancements in the understanding of nicotinic acetylcholine receptors. Her patent not only showcases her innovative spirit but also provides valuable tools for diagnosing and treating associated conditions. As a woman inventor, she continues to inspire future generations in the realms of science and innovation.