The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 19, 2013

Filed:

Dec. 01, 2005
Applicants:

Jogeshwar Mukherjee, Irvine, CA (US);

Ramaiah Pichika, Oregon, CA (US);

Steven Potkin, Irvine, CA (US);

Frances Leslie, Irvine, CA (US);

Sankha Chattopadhyay, Bidhannagar, IN;

Inventors:

Jogeshwar Mukherjee, Irvine, CA (US);

Ramaiah Pichika, Oregon, CA (US);

Steven Potkin, Irvine, CA (US);

Frances Leslie, Irvine, CA (US);

Sankha Chattopadhyay, Bidhannagar, IN;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 401/12 (2006.01);
U.S. Cl.
CPC ...
Abstract

Contemplated compositions and methods are employed to bind in vitro and in vivo to an α4β2 nicotinic acetylcholine receptor in a highly selective manner. Where such compounds are labeled, compositions and methods employing such compounds can be used for PET and SPECT analysis. Alternatively, and/or additionally contemplated compounds can be used as antagonists, partial agonists or agonists in the treatment of diseases or conditions associated with α4ββ2 dysfunction.


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