Company Filing History:
Years Active: 2014-2016
Title: Filippo Mori: Innovator in Plasma Protein Purification
Introduction
Filippo Mori is a distinguished inventor based in Lucca, Italy. He has made significant contributions to the field of biochemistry, particularly in the purification of plasma proteins. With a total of 2 patents, his work focuses on developing efficient and scalable processes for therapeutic applications.
Latest Patents
Mori's latest patents include a process for highly selective purification of two plasma proteins: von Willebrand factor (vWF) and fibronectin (Fn). This invention describes a chromatographic purification process that allows for the production of highly purified vWF and Fn from a biological fraction enriched in these proteins. The process is designed to be easily scalable to an industrial level, utilizing a strong anionic exchange resin. The concentrates produced exhibit high specific activity and low levels of contaminant proteins, making them particularly suitable for therapeutic use.
Another notable patent is the process for the preparation of a virus-inactivated FV concentrate starting from human plasma. This invention provides a simple and cost-effective method for purifying FV, which is scalable to industrial levels. The process involves two anion exchange chromatography steps, effectively separating FV from other plasma components. Additionally, it includes viral inactivation and removal steps, enhancing the safety of the final product without compromising the overall recovery of FV.
Career Highlights
Filippo Mori is currently associated with Kedrion S.p.a., a company known for its expertise in the production of plasma-derived therapies. His work at Kedrion has been instrumental in advancing the field of plasma protein purification.
Collaborations
Mori collaborates with notable colleagues, including Ilaria Nardini and Claudio Farina. Their combined expertise contributes to the innovative research and development efforts within the company.
Conclusion
Filippo Mori's contributions to the purification of plasma proteins have significant implications for therapeutic applications. His innovative processes not only enhance the efficiency of protein purification but also ensure the safety and efficacy of the final products.