The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 23, 2016
Filed:
Jan. 19, 2010
Applicants:
Filippo Mori, Lucca, IT;
Ilaria Nardini, Barga, IT;
Claudio Farina, Pisa, IT;
Claudia Nardini, Lucca, IT;
Inventors:
Filippo Mori, Lucca, IT;
Ilaria Nardini, Barga, IT;
Claudio Farina, Pisa, IT;
Claudia Nardini, Lucca, IT;
Assignee:
KEDRION S.P.A., , IT;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 14/78 (2006.01); C07K 14/755 (2006.01);
U.S. Cl.
CPC ...
C07K 14/755 (2013.01); C07K 14/78 (2013.01);
Abstract
There is described a chromatographic purification process that allows highly purified von Willebrand factor (vWF) and Fibronectin (Fn) to be obtained, starting from a biological fraction enriched in vWF and Fn and easily scaled up to industrial level. Chromatographic purification was obtained by a strong anionic exchange resin. The concentrates obtained have a high specific activity and, given the low content of contaminant proteins, are particularly suitable for therapeutic use.