Ferran Gimenez Guasch

Title: Ferran Gimenez Guasch: Innovator in Selective COX-2 Inhibitors

Introduction

Ferran Gimenez Guasch is a notable inventor based in Barcelona, Spain. He has made significant contributions to the field of medicinal chemistry, particularly in the development of selective inhibitors for cyclooxygenase-2 (COX-2). His work focuses on creating compounds that can effectively treat inflammation and related diseases.

Latest Patents

Ferran Gimenez Guasch holds a patent for "Substituted imidazo 1,2a}azines as selective inhibitors of COX-2." This invention refers to new compounds of formula (I), wherein A and B are selected from the group consisting of N and CH, with the condition that when A is N, B is N. R is selected from the group consisting of CH and NH. R and R are selected from the group consisting of H, CH, Br, Cl, COCH, and OCH. Additionally, R1, R2, and R3 are selected from the group consisting of H, F, Cl, Br, (C1-C3)-alkyl, trifluoromethyl, (C1-C3)-alkoxy, and trifluoromethoxy. These compounds are prepared by the reaction of a substituted aminoazine with a substituted 2-bromo-2-(4-R-sulfonylphenyl)-1-phenylethanone in a polar solvent. The compounds exhibit high selectivity in inhibiting COX-2 over COX-1, making them useful for treating inflammation and cyclooxygenase-mediated diseases while minimizing ulcerogenic effects. He has 1 patent to his name.

Career Highlights

Ferran Gimenez Guasch is associated with Laboratorios Salvat, S.A., where he continues to innovate in the pharmaceutical sector. His work has been instrumental in advancing therapeutic options for patients suffering from inflammatory conditions.

Collaborations

Ferran has collaborated with notable colleagues such as Carles Farrerons Gallemi and Ignacio-José Miquel Bono. Their combined expertise has contributed to the successful development of new pharmaceutical compounds.

Conclusion

Ferran Gimenez Guasch is a prominent figure in the field of medicinal chemistry, recognized for his innovative work on selective COX-2