Fei Xiao

Title: Fei Xiao: Innovator in Chiral Purity Lactam Synthesis

Introduction

Fei Xiao is a notable inventor based in Jiangsu, China. He has made significant contributions to the field of pharmaceutical chemistry, particularly in the synthesis of chiral compounds. His innovative methods have the potential to enhance the efficiency and cost-effectiveness of drug production.

Latest Patents

Fei Xiao holds a patent for a method of preparing a high chiral purity lactam intermediate and brivaracetam. This invention discloses a method that involves reducing a compound to lactam intermediate D in a solvent through hydrogenation reduction using a heavy metal catalyst and a chiral inducer. The synthesis route is characterized by its short duration, mild reaction conditions, simple post-treatment, high reaction yield, good chiral selectivity, and low production cost. The conversion rate of the compound in the reaction is 81%, and the DE value of the compound D exceeds 99.0%, making it suitable for industrial production.

Career Highlights

Throughout his career, Fei Xiao has worked with prominent companies in the pharmaceutical industry, including Yangzhou Aoruite Pharmaceutical Co., Ltd. and Yangzhou Lianao Biomedical Co., Ltd. His work has been instrumental in advancing the methodologies used in drug synthesis.

Collaborations

Fei Xiao has collaborated with esteemed colleagues such as Zhenpeng Yu and Guoping Wang. These partnerships have contributed to the development of innovative solutions in the field of pharmaceutical chemistry.

Conclusion

Fei Xiao's contributions to the field of chiral synthesis and his innovative patent demonstrate his commitment to advancing pharmaceutical science. His work not only enhances the efficiency of drug production but also paves the way for future innovations in the industry.