Location History:
- Manchester, GB (2023)
- Didsbury Village Greater Manchester, GB (2024)
Company Filing History:
Years Active: 2023-2025
Title: Inventor Federica Sotgia: Pioneering Cancer Therapeutics
Introduction
Federica Sotgia is an accomplished inventor based in Manchester, GB, known for her significant contributions to the field of cancer therapeutics. With a remarkable portfolio of five patents, her work focuses on innovative treatments that target cancer growth and improve patient outcomes.
Latest Patents
Among Sotgia's notable inventions are her latest patents, which include selective CDK 4/6 inhibitor cancer therapeutics. This disclosure describes selective and potent CDK 4/6 inhibitors that demonstrate advantageous inhibition of cancer growth at low concentrations. The compounds relate to substituted pyridopyrimidine derivatives of Palbociclib, featuring a fatty acid moiety. They have a general formula wherein various substituents provide a wide range of customizable pharmaceutical applications for the treatment, prevention, and amelioration of cancer.
Another significant patent involves the use of azithromycin and roxithromycin derivatives as senolytic drugs. This disclosure highlights their efficacy as senolytic agents, utilizing BrdU to induce senescence in human fibroblast cell lines. Methods of screening for senolytic activity were developed, revealing that azithromycin significantly targets senescent cells, with a nearly 25-fold reduction in their presence.
Career Highlights
Federica Sotgia works with Lunella Biotech, Inc., where she continues to push the boundaries of cancer research and therapeutics. Her innovative approaches and extensive research have solidified her reputation in the scientific community, making her a prominent figure in the field of medical innovation.
Collaborations
Sotgia has collaborated with esteemed colleagues such as Michael P. Lisanti and Jussi Kangasmetsa. These partnerships have fostered an environment of creativity and knowledge-sharing, propelling forward new ideas and breakthroughs in cancer treatment.
Conclusion
In conclusion, Federica Sotgia stands as a vital contributor to the fight against cancer through her inventions and innovative research. Her patents not only pave the way for advancing cancer therapeutics but also inspire further exploration and discovery in the field. As she continues her work at Lunella Biotech, Sotgia exemplifies the transformative power of innovation in medicine.