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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 12358920 B1

PDFFull Text
Date of Patent:
Jul. 15, 2025

Filed:

Dec. 15, 2020

Substituted pyrrolo[2,3-d]pyrimidines as selective cdk 4/6 inhibitors

Applicant:

Lunella Biotech, Inc., Ottawa, CA;

Inventors:

Michael P. Lisanti, Didsbury Village, GB;

Federica Sotgia, Didsbury Village, GB;

Jussi Kangasmetsa, Cambridge, GB;

Luma G. Magalhães, Salford, GB;

Assignee:

LUNELLA BIOTECH, INC., Ontario, CA;

Attorney:

Nixon & Vanderhye P.C.

Primary Examiner:

Douglas M Willis

Int. Cl.
CPC ...
A61K 31/519 (2006.01); A61K 9/20 (2006.01); A61P 15/00 (2006.01); A61P 35/00 (2006.01); A61P 35/04 (2006.01); C07D 487/04 (2006.01);
U.S. Cl.
CPC ...
C07D 487/04 (2013.01); A61K 9/20 (2013.01); A61P 15/00 (2018.01); A61P 35/00 (2018.01); A61P 35/04 (2018.01);
Abstract

This disclosure describes selective and potent CDK 4/6 inhibitors that show advantageous inhibition of cancer growth, even at low concentrations. This class of anti-cancer CDK 4/6 inhibitors are substituted pyrrolopyrimidine compounds of formula IA, having a fatty acid moiety. These compounds may be used as pharmaceutical compounds for anti-cancer therapies, and are useful for the treatment, prevention and/or amelioration of cancer.

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Quick Actions:

Lisanti, Michael. (2025). Substituted pyrrolo[2,3-d]pyrimidines as selective cdk 4/6 inhibitors (U.S. Patent No. 12358920). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/12358920

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