The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 23, 2024
Filed:
Jun. 10, 2021
Applicant:
Lunella Biotech, Inc., Ottawa, CA;
Inventors:
Michael P. Lisanti, Didsbury Village Greater Manchester, GB;
Federica Sotgia, Didsbury Village Greater Manchester, GB;
Jussi Kangasmetsa, Cambridge, GB;
Assignee:
LUNELLA BIOTECH, INC., Ontario, CA;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 487/14 (2006.01); C07D 487/20 (2006.01);
U.S. Cl.
CPC ...
C07D 487/14 (2013.01); C07D 487/20 (2013.01);
Abstract
This disclosure describes embodiments of selective and potent CDK 4/6 inhibitors that show advantageous inhibition of cancer growth, even at low concentrations. As described herein, compounds of the present approach comprise substituted pyridinylpiperazine-pyrrolopyrimidine compounds having a fatty acid moiety. The compounds described herein may be used as pharmaceutical compounds for anti-cancer therapies, and are useful for the treatment, prevention and/or amelioration of cancer. Formula (a)