Faqing Wu

Title: Faqing Wu: Innovator in L-Valine Production

Introduction

Faqing Wu is a prominent inventor based in Tianjin, China. He has made significant contributions to the field of biotechnology, particularly in the production of amino acids through fermentation processes. His innovative work has led to the development of a genetically engineered strain that enhances the yield of L-valine, an essential amino acid.

Latest Patents

Faqing Wu holds a patent for a genetically engineered strain with a high yield of L-valine and a method for producing L-valine by fermentation. This patent describes a strain derived from W3110, which incorporates several genetic modifications to optimize L-valine production. Key modifications include the insertion of an acetolactate synthase gene, the overexpression of a ppGpp 3'-pyrophosphate hydrolase mutant gene, and the deletion of specific genes related to lactate dehydrogenase and fumaric acid reductase. Additionally, the fermentation method has been improved through a two-stage dissolved oxygen control, resulting in increased L-valine titer and sugar-acid conversion rates.

Career Highlights

Faqing Wu is affiliated with Tianjin University of Science and Technology, where he conducts research and development in biotechnology. His work has garnered attention for its practical applications in the production of amino acids, which are vital for various industrial and pharmaceutical processes.

Collaborations

He has collaborated with notable colleagues, including Xixian Xie and Heyun Wu, to advance research in the field of genetic engineering and fermentation technology. Their combined efforts have contributed to the successful development of innovative biotechnological solutions.

Conclusion

Faqing Wu's contributions to the field of biotechnology, particularly in L-valine production, highlight the importance of innovation in addressing industrial challenges. His patented methods and collaborative efforts continue to pave the way for advancements in fermentation technology.