Fan Long

Title: The Innovative Contributions of Fan Long

Introduction

Fan Long is an accomplished inventor based in Bridgewater, NJ (US). He has made significant contributions to the field of gene expression level detection through his innovative patent. His work is particularly relevant in the context of genomic research and biotechnology.

Latest Patents

Fan Long holds a patent titled "Probe correction for gene expression level detection." This patent involves a method where individual probes on micro-arrays are re-scaled and corrected using a set of probe-dependent coefficients derived from genomic-DNA hybridization signals. The dynamic range for genomic DNA binding is determined by measuring a concentration signal curve. Signals for each probe are measured during multiple hybridizations within a linear range. Concentration-insensitive probes are identified for two sets of experiments, and probes are discarded based on a threshold compared to their standard deviation divided by their average in each set. The correction coefficients are then utilized to calculate a corrected intensity for each probe. Probes with high uncertainty are discarded, and a weighting factor along with an uncertainty factor is determined for each probe. Ultimately, a call for each gene is made, categorizing it as absent, marginal, or present.

Career Highlights

Fan Long is currently employed at Syngenta Participations AG, where he continues to apply his expertise in biotechnology and genomics. His innovative approach to probe correction has the potential to enhance the accuracy of gene expression analysis, which is crucial for various applications in research and medicine.

Collaborations

Fan Long collaborates with notable colleagues, including Yiping Fan and Hur-Song Chang. Their combined expertise contributes to advancing research in the field of gene expression and biotechnology.

Conclusion

Fan Long's contributions to the field of gene expression level detection through his innovative patent demonstrate his commitment to advancing biotechnology. His work not only enhances the accuracy of genomic research but also paves the way for future innovations in the field.