Company Filing History:
2 out of 5,072 
1 out of 23 
1 out of 1 Years Active: 2016-2017
Title: Ez-Zoubir Amri: Innovator in Human Brown Adipocyte Research
Introduction
Ez-Zoubir Amri is a notable inventor based in Nice, France. He has made significant contributions to the field of adipocyte research, particularly in understanding human brown adipocytes and their role in energy homeostasis. With a total of 2 patents, his work has implications for treating obesity and related metabolic disorders.
Latest Patents
Amri's latest patents include the establishment of a human brown adipocyte line and a method for differentiation from an hMADS cell line. This invention focuses on a functional population of human brown adipocytes, characterized by higher expression levels of UCP1, CIDEA, CPT1B, and Bc12, while showing lower expression of Bax. Additionally, it outlines methods for differentiating hMADS cells into these brown adipocytes and converting white adipocytes into brown adipocytes. Another significant patent involves UCP1-inducing agents for treating disorders related to energy homeostasis, such as obesity and metabolic syndrome. This invention comprises compositions that upregulate UCP1 expression, providing a potential therapeutic avenue for these conditions.
Career Highlights
Throughout his career, Amri has worked with esteemed institutions, including the National Centre for Scientific Research (Centre National De La Recherche Scientifique) and the University of Nice Sophia Antipolis. His research has been pivotal in advancing the understanding of adipocyte biology and its implications for health.
Collaborations
Amri has collaborated with notable colleagues such as Gérard Paul Ailhaud and Christian Jean Lucien Dani. Their joint efforts have contributed to the advancements in the field of adipocyte research.
Conclusion
Ez-Zoubir Amri's innovative work in the field of human brown adipocytes has the potential to impact the treatment of obesity and metabolic disorders significantly. His patents reflect a commitment to advancing scientific knowledge and improving health outcomes.
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