Eun Kyoung Bang

Title: Eun Kyoung Bang: Innovator in Lipid Nanoparticle Technology

Introduction

Eun Kyoung Bang is a prominent inventor based in Seoul, South Korea. He has made significant contributions to the field of pharmaceutical compositions, particularly in the development of lipid nanoparticles for drug delivery. With a total of 4 patents, his work focuses on enhancing the efficacy of nucleic acid drugs.

Latest Patents

One of his latest patents involves a pharmaceutical composition of lipid nanoparticles designed for delivering nucleic acid drugs containing trehalose derivatives. This innovative composition stabilizes nucleic acid drugs and enhances their delivery in vivo. The lipid nanoparticles include various types of nucleic acid drugs, such as mRNA-based vaccines and RNA for immune boosters. The lipid component consists of a trehalose-based lipid, an ionizable lipid, a phospholipid, a PEG-lipid, and a structure-maintaining lipid. This structure-maintaining lipid can replace commonly used cholesterol with derivatives of lithocholic acid, glycyrrhetinic acid, or diosgenin. These lipid nanoparticles can serve as either vaccines or therapeutic agents, depending on the nucleic acid drug utilized.

Another significant patent focuses on compounds that act as near-infrared fluorescent probes selectively binding to tau aggregates. This invention includes a method for preparing the compound and a tau-targeting near-infrared fluorescent probe. The composition is intended for detecting tau fiber proteins, which are crucial for the early diagnosis of tauopathies, including Alzheimer's disease. Notably, the compound demonstrates high selectivity for tau aggregates and does not bind to amyloid beta proteins.

Career Highlights

Eun Kyoung Bang has worked with notable organizations, including the Korea Institute of Science and Technology and SML Biopharm Co., Ltd. His research and innovations have significantly impacted the pharmaceutical industry, particularly in drug delivery systems.

Collaborations

He has collaborated with esteemed colleagues such as Gyo Chang Keum and Ghil Soo Nam, contributing to advancements in his field.

Conclusion

Eun Kyoung Bang's innovative work in lipid nanoparticle technology and drug delivery systems showcases his commitment to advancing medical science. His patents reflect a deep understanding of pharmaceutical compositions and their potential to improve therapeutic outcomes.