Chevy Chase, MD, United States of America

Ettore Appella

USPTO Granted Patents = 18 


 

Average Co-Inventor Count = 5.3

ph-index = 8

Forward Citations = 116(Granted Patents)


Company Filing History:


Years Active: 1996-2011

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18 patents (USPTO):Explore Patents

Title: **Inventor Ettore Appella: A Pioneer in Retroviral Research**

Introduction

Ettore Appella, an accomplished inventor based in Chevy Chase, MD, has made significant strides in the field of medicinal chemistry, particularly in developing therapeutic agents against retroviral infections. With a portfolio of 18 patents, his innovative contributions are invaluable in the fight against diseases such as HIV.

Latest Patents

Among his most recent patents are two notable inventions: the first focuses on "Acythiols and component thiol compositions as anti-HIV and anti-retroviral agents." This patent describes certain thiol and acylthiol compounds that effectively inhibit retrovirus growth by targeting the highly conserved zinc finger regions of essential viral proteins. These compounds are instrumental not only in treating retroviral infections, like HIV, but also have applications in vaccine development and the prevention and detection of retroviruses.

The second patent, titled "Thiolesters and uses thereof," delves into a novel family of thiolesters and their numerous applications. This invention also encompasses viricidal compounds and pharmaceutical formulations containing these thiolesters, as well as thiolester-inactivated viruses and thiolester-complexed viral proteins, showcasing a broad potential for therapeutic use.

Career Highlights

Throughout his career, Appella has been associated with important organizations such as the United States of America, represented by the Secretary of the Department of Health and Human Services, and the Department of Health. His work has played a crucial role in advancing public health through innovative research and development.

Collaborations

Ettore Appella has collaborated with notable colleagues, including Teizo Yoshimura and Edward J. Leonard. These partnerships have contributed to his success, fostering an environment for groundbreaking inventions in the field of anti-retroviral therapies.

Conclusion

Ettore Appella stands out as a key figure in modern medicinal research with his extensive patent portfolio and impactful collaborations. His ongoing work continues to pave the way for advancements in the treatment of retroviral diseases, highlighting the importance of innovation in improving global health.

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