The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 22, 2005

Filed:

Mar. 30, 1989
Applicants:

Teizo Yoshimura, Frederick, MD (US);

Elizabeth A. Robinson, Bethesda, MD (US);

Ettore Appella, Chevy Chase, MD (US);

Edward J. Leonard, Chevy Chase, MD (US);

Inventors:

Teizo Yoshimura, Frederick, MD (US);

Elizabeth A. Robinson, Bethesda, MD (US);

Ettore Appella, Chevy Chase, MD (US);

Edward J. Leonard, Chevy Chase, MD (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K014/00 ;
U.S. Cl.
CPC ...
Abstract

Pure peptide products, derived from either human glioma cell line U-105MG or human peripheral blood mononuclear leukocytes are provided; the products have a molecular mass of about 8,400 daltons, and the products exhibit optimal monocyte chemotactic activity at a concentration of 1 nM. The cloning of full length cDNA for the peptide products is also provided, as well as recombinant methods for the production of monocyte chemoattractant products. Methods of treating infection and neoplasms in a human body with such peptides and monocyte chemoattractant products are additionally provided, as well as pharmaceutical compositions for the same.


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