Company Filing History:
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Years Active: 1985-2002
Title: Ernst Hetzl: Innovator in Biochemical Purification
Introduction
Ernst Hetzl is a notable inventor based in Vienna, Austria. He has made significant contributions to the field of biochemical purification, holding a total of 4 patents. His work focuses on methods that enhance the purification processes of important biological compounds.
Latest Patents
One of Hetzl's latest patents is a method for the purification of antithrombin III using an anion exchanger. This innovative method involves adsorbing the AT III/heparin complex or the AT III/heparinoid complex on an anion exchanger material. The process further includes separating the AT III from the adsorbed complex by elution with a buffer that has a pH ranging from 8.5 to 10.5 and a conductivity between 10 and 60 mS. Another significant patent is the method of producing lys-plasminogen. This process prepares lys-plasminogen from blood plasma or blood plasma products, ensuring a specific activity of at least 17.5 caseinolytic units/mg protein. The method involves several steps, including phosphate precipitation, ethanol precipitation, and the use of an immobilized lysine affinity column for purification.
Career Highlights
Throughout his career, Hetzl has worked with prominent companies such as Immuno Aktiengesellschaft and Immuno Aktiengesellschaft für Chemisch-Medizinische Produkte. His expertise in biochemical processes has made him a valuable asset in these organizations.
Collaborations
Hetzl has collaborated with notable individuals in his field, including Yendra Linnau and Johann J. Eibl. These partnerships have contributed to the advancement of his research and innovations.
Conclusion
Ernst Hetzl's contributions to biochemical purification through his patents and collaborations highlight his role as an influential inventor in the field. His innovative methods continue to impact the industry positively.