The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 28, 2002
Filed:
May. 26, 2000
Applicant:
Inventors:
Yendra Linnau, Vienna, AT;
Ernst Hetzl, Vienna, AT;
H. Peter Matthiessen, Vienna, AT;
Silvia Neppl, Vienna, AT;
Wolfgang Schönhofer, St. Pölten, AT;
Hans-Peter Schwarz, Vienna, AT;
Assignee:
Baxter Aktiengesellschaft, Vienna, AT;
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12N 9/74 ; A61K 3/514 ; A23J 1/100 ;
U.S. Cl.
CPC ...
C12N 9/74 ; A61K 3/514 ; A23J 1/100 ;
Abstract
A method of purifying antithrombin III (AT III) from a starting material containing an AT III/heparin complex or an AT III/heparinoid complex is disclosed. First, the method comprises adsorbing the AT III/heparin complex or the AT III/heparinoid complex on an anion exchanger material. Second, the method involves separating the AT III from the adsorbed AT III/heparin complex or an AT III/heparinoid complex by elution with a buffer having a pH ranging from 8.5 to 10.5 and a conductivity between 10 and 60 mS.