Company Filing History:
2 out of 656 
1 out of 340 
1 out of 18 Years Active: 1997-1999
Title: The Innovations of Ernst-Guenter Afting
Introduction
Ernst-Guenter Afting is a notable inventor based in Marburg, Germany. He has made significant contributions to the field of biochemistry, particularly in the development of peptide plasminogen activators. With a total of two patents to his name, Afting's work has advanced the understanding and application of tissue plasminogen activator (tPA).
Latest Patents
Afting's latest patents focus on novel polypeptide compositions derived from the amino acid sequence of tissue plasminogen activator. These innovations provide improved properties over natural tPA, including enhanced specific activity and reduced response to inhibition by plasminogen activator inhibitors. His work also emphasizes modifications to the N- or C-termini of the polypeptides, which lead to reduced fibrin stimulation of plasminogenolytic activity and enhanced affinity to fibrin surfaces.
Career Highlights
Throughout his career, Afting has worked with prominent companies in the biotechnology sector. He has been associated with Chiron Corporation and Behringwerke Aktiengesellschaft, where he contributed to various research and development projects. His expertise in peptide technology has positioned him as a valuable asset in the field.
Collaborations
Afting has collaborated with notable professionals in his field, including Nancy L. Haigwood and Guy T. Mullenbach. These collaborations have further enriched his research and have led to advancements in the understanding of plasminogen activators.
Conclusion
Ernst-Guenter Afting's contributions to the field of biochemistry, particularly through his patents on peptide plasminogen activators, highlight his innovative spirit and dedication to advancing medical science. His work continues to influence the development of therapeutic agents that can improve patient outcomes.