Introduction: Ernest W. Yankee, a prominent inventor from Portage, MI, is recognized for his significant contributions to the field of medicine and chemistry. With a remarkable portfolio of 47 patents, Yankee's work has had a lasting impact on various pharmaceutical applications.

Latest Patents: Among his latest patents, two stand out for their innovative potential. The first is titled "Pyrrolizidine-3-ones," which introduces 2,3-didehydro-5-oxopyrrolizidinones and indolizidinones that serve as lipid-altering and anti-atherosclerotic agents. The second patent, "Aryl-cis-13-PGF Compounds," presents analogs of prostaglandins featuring a cis configuration between C-13 and C-14. These analogs not only showcase prostaglandin-like activity but also serve important pharmacological purposes such as lowering blood pressure, inducing labor at term, regulating reproductive cycles, and providing gastric antisecretory action.

Career Highlights: Ernest W. Yankee's career has been marked by groundbreaking research and pioneering inventions. His extensive work has contributed to advancements in both medicinal chemistry and drug development, underscoring his status as a leading figure in his field.

Collaborations: Throughout his career, Yankee has had the privilege of collaborating with notable individuals, including his former coworker Ronald H. Rynbrandt, who is remembered for his contributions to their shared projects.

Conclusion: Ernest W. Yankee's innovative spirit and dedication to research have positioned him as a noteworthy inventor in the realm of pharmaceuticals. With his extensive patent portfolio, his work continues to influence the development of new medical therapies, benefiting countless individuals in the process.

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