Eric J Berns

Title: The Innovative Contributions of Eric J Berns

Introduction

Eric J Berns is a notable inventor based in Park Ridge, IL (US), recognized for his significant contributions to the field of microfluidics and cell analysis. With a total of 3 patents, Berns has made strides in developing technologies that enhance the manipulation and analysis of live cells.

Latest Patents

One of Berns' latest patents is a microfluidic device designed for live cell manipulation and analysis. This innovative cell analysis system features a multi-layer microfluidic device that includes a layer of microfluidic channels, a layer of microwells, a membrane with nanochannels, and a layer of extraction chambers. The design allows for the culturing of cells that are either adhered to the membrane or suspended in the microwells. The membrane is specifically configured to facilitate the diffusion of substances into the extraction chambers. Additionally, the system incorporates a top conductive layer and a bottom conductive layer, enabling the application of an electroporation pulse for enhanced cellular assays. Another significant patent involves cellular assays with a molecular endpoint measured by SAMDI mass spectrometry. This disclosure presents a cell-based, label-free assay that is compatible with high-throughput screening (HTS) and quantitatively reports on enzyme activities by measuring mass changes of substrates using MALDI-mass spectrometry.

Career Highlights

Berns is affiliated with Northwestern University, where he continues to advance research in microfluidics and cell analysis. His work has garnered attention for its potential applications in various scientific fields, particularly in biomedical research.

Collaborations

Throughout his career, Berns has collaborated with esteemed colleagues, including Milan Mrksich and Samuel I Stupp, further enhancing the impact of his research and innovations.

Conclusion

Eric J Berns exemplifies the spirit of innovation through his groundbreaking work in microfluidics and cell analysis. His contributions are paving the way for advancements in scientific research and technology.