Company Filing History:
Years Active: 1998-2007
Title: Eric E Adam: Innovator in Protein Splicing Technologies
Introduction
Eric E Adam is a notable inventor based in Beverly, MA (US), recognized for his contributions to the field of protein splicing. He holds a total of 3 patents that focus on innovative methods for controlling intein splicing, which have significant implications in biotechnology and drug delivery.
Latest Patents
Among his latest patents is a groundbreaking invention titled "Screening and use of agents which block or activate intein splicing utilizing natural or homologous exteins." This patent outlines selection systems and methods for screening agents that control the splicing of inteins in their native host proteins or homologous exteins. The invention provides positive genetic selection systems for screening agents that inhibit or activate protein splicing. These systems involve a host cell with a chromosomal gene encoding either a drug-resistant or wild-type target enzyme, alongside a plasmid-borne gene that encodes a drug-sensitive form of the target enzyme. The inhibition or activation of splicing by a given reagent can lead to the survival or death of the host cell, showcasing the potential for applications in controlling protein expression and drug delivery.
Career Highlights
Eric E Adam is currently associated with New England Biolabs, Inc., where he continues to advance research in molecular biology and biotechnology. His work has contributed to the understanding of intein splicing mechanisms and their applications in various scientific fields.
Collaborations
Throughout his career, Eric has collaborated with esteemed colleagues, including Francine B Perler and Donald G Comb, who have also made significant contributions to the field of molecular biology.
Conclusion
Eric E Adam's innovative work in intein splicing technologies highlights his role as a leading inventor in the biotechnology sector. His patents not only advance scientific knowledge but also pave the way for new applications in drug development and protein engineering.