Location History:
- Urbana, IL (US) (1989 - 2011)
- San Clemente, CA (US) (2012 - 2022)
Company Filing History:
9 out of 10 
7 out of 2,343 
7 out of 15,475 
Years Active: 1989-2025
Title: Enrico Gratton: Pioneering Innovations in Hyperspectral Imaging
Introduction
Enrico Gratton, based in San Clemente, CA, is a renowned inventor and researcher celebrated for his significant contributions to the field of hyperspectral imaging. With a remarkable portfolio of 22 patents, his work has profoundly impacted scientific imaging technologies and cellular metabolic studies.
Latest Patents
Among Gratton's latest innovations is a patented system and method for hyperspectral imaging in highly scattering media utilizing the spectral phasor approach. This imaging system features an excitation light source, a directing element to focus light on a sample, a detector for measuring incoming light, and a specialized filter cavity that accommodates two filters. The integration of a processing unit facilitates the reception and analysis of image data, resulting in high-quality imaging capabilities.
Another groundbreaking patent involves a phasor method applied to fluorescence lifetime microscopy, aimed at discriminating metabolic states of cells in living tissues. This label-free imaging technique provides insights into stem cell metabolism by identifying and mapping intrinsic fluorescence biomarkers such as collagen and NADH within germ cells. The sensitivity of the phasor approach enables researchers to sense minimal alterations in cellular redox states and predicts cell fate through the differentiation process.
Career Highlights
Enrico Gratton has had a distinguished career, with notable affiliations including I.S.S. (USA), Inc. and the University of Illinois. His expertise lies in developing innovative solutions that merge imaging techniques with biological research, fostering advancements in the understanding of cell metabolism and tissue differentiation.
Collaborations
Throughout his career, Gratton has collaborated with several esteemed colleagues, including Beniamino Barbieri and Sergio Fantini. These partnerships have been instrumental in advancing research projects and enhancing the impact of their collective work in the scientific community.
Conclusion
Enrico Gratton’s innovations in hyperspectral imaging and fluorescence lifetime microscopy exemplify the fusion of technology with biological research. His 22 patents underscore his role as a leading inventor, contributing to advancements that promise to enhance our understanding of cellular processes and metabolic states. Gratton’s ongoing research and collaborations continue to pave the way for future breakthroughs in this exciting field.