Location History:
- Swampscott, MA (US) (1994)
- Andover, MA (US) (1993 - 2018)
Company Filing History:
Years Active: 1993-2018
Title: Innovations and Contributions of Ellen P. Guthrie
Introduction
Ellen P. Guthrie is a prominent inventor based in Andover, MA (US). She has made significant contributions to the field of biochemistry, particularly in the development of methods and reagents for antibody modification. With a total of 10 patents to her name, her work has had a substantial impact on the scientific community.
Latest Patents
One of her latest patents focuses on "Deglycosylation reagents and methods." This invention provides compositions and methods for efficiently preparing a completely deglycosylated antibody, measuring efficiency in terms of the relative amounts of reagents in both soluble and lyophilized forms, as well as the time and temperature of the reaction. Additionally, her methods allow for the separation of substantially all N-linked glycans from a glycosylated antibody while preserving the functionality of the antibody. These methods are compatible with glycan labeling and protease digestion without the need for prior purification steps. Another notable patent describes methods and compositions related to a newly identified polypeptide family, each member exhibiting O-glycosidase activity and specific sequence characteristics. This family of enzymes can be utilized for cleaving O-linked glycans and for the synthesis of neoglycopeptides or neoglycoproteins.
Career Highlights
Ellen P. Guthrie is currently associated with New England Biolabs, Inc., where she continues to innovate and contribute to advancements in biochemistry. Her work has been recognized for its practical applications in the field, particularly in antibody research and development.
Collaborations
Throughout her career, Ellen has collaborated with notable colleagues, including Christopher H. Taron and David Landry. These collaborations have further enhanced her research and contributed to the success of her inventions.
Conclusion
Ellen P. Guthrie's contributions to the field of biochemistry through her innovative patents and collaborations highlight her role as a leading inventor. Her work continues to influence the scientific community and pave the way for future advancements in antibody research.
Inventor’s Patent Attorneys refers to legal professionals with specialized expertise in representing inventors throughout the patent process. These attorneys assist inventors in navigating the complexities of patent law, including filing patent applications, conducting patent searches, and protecting intellectual property rights. They play a crucial role in helping inventors secure patents for their innovative creations.