The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 15, 2008
Filed:
Feb. 20, 2004
Applicants:
Ellen Guthrie, Andover, MA (US);
Theodore Davis, Boxford, MA (US);
Jack Benner, Ii, South Hamilton, MA (US);
Inventors:
Ellen Guthrie, Andover, MA (US);
Theodore Davis, Boxford, MA (US);
Jack Benner, II, South Hamilton, MA (US);
Assignee:
New England Biolabs, Inc., Ipswich, MA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/42 (2006.01); C12P 21/06 (2006.01); C12N 9/16 (2006.01);
U.S. Cl.
CPC ...
Abstract
Compositions for an alkaline phosphatase and methods for over-expression and purification of thermolabile Antarctic phosphatase (TAP) are provided. Uses for TAP include dephosphorylation of nucleic acids, sugars, peptides and proteins. TAP as described herein has advantages over phosphatases from other sources with respect to thermolability at 65° C. and efficiency of dephosphorylation activity at approximately neutral pH.