Company Filing History:
Years Active: 2023-2024
Title: Ella Zeldich: Innovator in Gene Expression Modulation
Introduction
Ella Zeldich is a prominent inventor based in Boston, MA, known for her significant contributions to the field of gene expression modulation. With a total of two patents to her name, she has made strides in understanding and enhancing the expression of the Klotho gene, which plays a crucial role in various biological processes.
Latest Patents
Zeldich's latest patents focus on innovative methods for increasing gene expression. One of her patents details compositions and methods for modulating gene expression, specifically targeting the Klotho gene. This patent outlines a method that involves administering a binding molecule to a cell, which binds to an RNA transcript transcribed from a chromosomal region near the Klotho gene. This approach aims to increase the expression of the Klotho gene, which is vital for cellular functions. Another patent elaborates on the use of CRISPR technology to enhance Klotho gene expression in human cells. This method includes introducing a CRISPR enzyme and a guide RNA that is complementary to a target sequence within or near the Klotho gene, thereby facilitating transcriptional activation.
Career Highlights
Throughout her career, Ella Zeldich has worked with notable companies such as Advantage Therapeutics, Inc. and Klogenix LLC. Her work in these organizations has allowed her to collaborate with leading experts in the field and contribute to groundbreaking research in gene expression.
Collaborations
Zeldich has collaborated with esteemed colleagues, including Ci-Di Chen and Carmela Abraham. These partnerships have enriched her research and expanded the impact of her innovations in gene expression.
Conclusion
Ella Zeldich is a trailblazer in the field of gene expression modulation, with her innovative patents paving the way for future advancements. Her work continues to influence the scientific community and holds promise for therapeutic applications.