Company Filing History:
Years Active: 2005-2006
Title: Innovations by Elizabeth J Wolffe
Introduction
Elizabeth J Wolffe is a prominent inventor based in Orinda, CA (US). She has made significant contributions to the field of biotechnology, particularly in the regulation of angiogenesis and gene expression. With a total of 2 patents, her work has implications for various therapeutic applications.
Latest Patents
One of her latest patents focuses on the regulation of angiogenesis with zinc finger proteins. This patent provides a variety of methods and compositions for regulating angiogenesis, which is crucial for treatments related to ischemia and wound healing. The methods utilize zinc finger proteins that bind to specific target sites in one or more VEGF genes. Additionally, nucleic acids encoding these zinc finger proteins are disclosed, along with methods for modulating the expression of VEGF genes. This innovation can be applied in therapeutic contexts that involve the regulation of endothelial cell growth. Another patent by Wolffe involves the modulation of gene expression using localization domains. This patent outlines methods and compositions that comprise localization domains, fusions of localization domains with DNA binding domains, and optional regulatory domains.
Career Highlights
Elizabeth J Wolffe is associated with Sangamo Biosciences, Inc., where she continues to advance her research and innovations. Her work has positioned her as a key figure in the biotechnology sector, contributing to the development of novel therapeutic strategies.
Collaborations
Throughout her career, Wolffe has collaborated with notable colleagues, including Edward J Rebar and Andrew Jamieson. These collaborations have further enriched her research and expanded the impact of her inventions.
Conclusion
Elizabeth J Wolffe's contributions to biotechnology through her patents and research have paved the way for advancements in therapeutic applications. Her innovative work continues to influence the field and offers promising solutions for various medical challenges.