Company Filing History:
Years Active: 2002-2004
Title: Eliana Drenkard: Innovator in Nucleic Acid Amplification Techniques
Introduction
Eliana Drenkard is a prominent inventor based in Cambridge, MA (US). She has made significant contributions to the field of molecular biology, particularly in the development of innovative techniques for nucleic acid amplification. With a total of 2 patents, her work has advanced the understanding and application of genetic analysis.
Latest Patents
Drenkard's latest patents include groundbreaking methods for broad range PCR amplification techniques. These methods and kits are designed to determine whether a nucleic acid sequence includes a particular allele of a polymorphic sequence. The focus is on two sets of primers that are specific for an allele, which are contacted with a nucleic acid sequence. One primer in each set is complementary to the polymorphic sequence at its 3′-terminal nucleotide and contains one or more mismatches in the five nucleotides adjacent to the 3′ terminus. This innovative approach allows for the preferential amplification of methods used to identify single nucleotide polymorphisms, which is essential for genomic mapping purposes.
Another significant patent by Drenkard involves virulence-associated nucleic acid sequences and their uses. This patent discloses bacterial virulence polypeptides and nucleic acid sequences encoding such polypeptides, along with methods for producing these polypeptides through recombinant techniques. Additionally, it provides methods for utilizing these polypeptides to screen for antibacterial or bacteriostatic compounds.
Career Highlights
Eliana Drenkard is currently associated with The General Hospital Corporation, where she continues to push the boundaries of research in her field. Her work has not only contributed to scientific knowledge but has also paved the way for practical applications in medicine and biotechnology.
Collaborations
Throughout her career, Drenkard has collaborated with esteemed colleagues, including Frederick M Ausubel and Michael Nicholas Mindrinos. These collaborations have further enriched her research and expanded the impact of her innovations.
Conclusion
Eliana Drenkard stands out as a key figure in the realm of molecular biology, with her innovative patents and collaborative efforts driving advancements in genetic analysis. Her contributions are vital to the ongoing evolution of biotechnology and its applications in healthcare.