The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 21, 2004
Filed:
Jan. 30, 2001
Frederick M. Ausubel, Newton, MA (US);
Michael Mindrinos, Menlo Park, CA (US);
Eliana Drenkard, Cambridge, MA (US);
The General Hospital Corporation, Boston, MA (US);
Abstract
Disclosed herein are methods and kits for determining whether a nucleic acid sequence includes a particular allele of a polymorphic sequence. These methods and kits focus on two sets of primers that are specific for an allele and are contacted with a nucleic acid sequence. One primer in each set is complementary to the polymorphic sequence at its 3′-terminal nucleotide and contains one or more mismatches in the five nucleotide adjacent to the 3′ terminus. The two sets of primers preferentially amplify methods are used to identify single nucleotide polymorphisms, for example, for genomic mapping purpose.