Company Filing History:
Years Active: 2007-2011
Title: Eileen Wilson: Innovator in Biochemical Crystallization
Introduction
Eileen Wilson is a prominent inventor based in Raritan, NJ (US). She has made significant contributions to the field of biochemistry, particularly in the area of crystallization techniques for important polypeptides. With a total of 3 patents to her name, her work has implications for drug discovery and development.
Latest Patents
Eileen Wilson's latest patents include innovative methods for preparing and utilizing refolded recombinant β-secretase crystals. The first patent focuses on methods for growing crystals of both the uncomplexed and complexed forms of β-secretase (BACE) polypeptide. This application also discusses the crystalline forms of uncomplexed BACE and the three-dimensional structure of BACE, as determined from the crystals. Additionally, it highlights the use of these crystalline forms to identify ligands, particularly inhibitors that can bind to and inhibit the enzymatic activity of BACE. The second patent elaborates on methods for making β-secretase co-crystals complexed with a ligand, further enhancing the understanding of BACE's structure and function.
Career Highlights
Eileen Wilson is currently associated with Schering Corporation, where she continues to advance her research in biochemistry. Her work has been instrumental in developing methods that improve the crystallization process, leading to more effective outcomes in the study of BACE polypeptide.
Collaborations
Eileen has collaborated with notable colleagues such as Brian M Beyer and Bruce A Malcolm. Their combined expertise has contributed to the successful development of her innovative patents.
Conclusion
Eileen Wilson's contributions to the field of biochemistry through her patents on β-secretase crystallization are noteworthy. Her work not only enhances scientific understanding but also paves the way for potential therapeutic advancements.