Eiji Tokunaga

Title: Eiji Tokunaga: Innovator in Protein Engineering

Introduction

Eiji Tokunaga is a notable inventor based in Kumamoto, Japan. He has made significant contributions to the field of protein engineering, particularly in the development of immunogenic variants of surface protective antigens.

Latest Patents

Eiji Tokunaga holds 5 patents that focus on a variant of the surface protective antigen SpaA protein. His latest patents describe a shortened form of SpaA, known as αSpaA, which involves the deletion of a portion of the SpaA protein to enhance protection from infection. The introduction of amino acid substitutions at specific sites in the amino acid sequence of SpaA or αSpaA results in a variant that is immunogenic and expressed in inclusion bodies. This innovative approach allows for easier recovery and purification of the variant protein.

Career Highlights

Eiji Tokunaga is affiliated with the Juridical Foundation the Chemo-sero-therapeutic Research Institute, where he continues to advance his research in protein engineering. His work has implications for vaccine development and therapeutic applications.

Collaborations

He has collaborated with notable colleagues, including Masashi Sakaguchi and Kazuo Matsuo, contributing to the advancement of their shared research goals.

Conclusion

Eiji Tokunaga's innovative work in protein engineering and his contributions to the field through his patents highlight his role as a significant inventor. His research continues to pave the way for advancements in immunogenic protein development.