Ee Lui Ang

Title: Innovations of Ee Lui Ang in Biocatalysis

Introduction

Ee Lui Ang is a prominent inventor based in Singapore, known for his significant contributions to the field of biocatalysis. With a total of 13 patents to his name, he has made remarkable advancements in the synthesis of pharmaceutical compounds, particularly armodafinil.

Latest Patents

One of his latest patents focuses on biocatalysts and methods for the synthesis of armodafinil. This invention relates to non-naturally occurring polypeptides that are useful for preparing armodafinil. The polypeptides are effective in carrying out biocatalytic conversions, such as transforming 2-(benzhydrylsulfinyl)acetamide into (−)-2-[(R)-(diphenylmethyl)sulfinyl]acetamide, or converting benzhydryl-thioacetic acid into (R)-2-(benzhydrylsulfinyl)acetic acid. These processes are crucial for producing armodafinil in enantiomeric excess.

Career Highlights

Ee Lui Ang is currently associated with Codexis, Inc., where he continues to innovate in the field of biocatalysis. His work has not only advanced scientific understanding but has also contributed to practical applications in the pharmaceutical industry.

Collaborations

He has collaborated with notable coworkers, including Ellen D Eberhard and Derek J Smith, who have contributed to his research and development efforts.

Conclusion

Ee Lui Ang's innovative work in biocatalysis and his numerous patents highlight his significant impact on the field of pharmaceutical synthesis. His contributions continue to pave the way for advancements in drug development and production.