Edwin Kiyoshi Oto

Title: Edwin Kiyoshi Oto: Innovator in Plasmid-Liposome Technology

Introduction

Edwin Kiyoshi Oto is a notable inventor based in Redwood City, CA (US). He has made significant contributions to the field of biotechnology, particularly in the development of plasmid-liposome complexes for transfection. With a total of 2 patents to his name, Oto's work is paving the way for advancements in genetic engineering and therapeutic applications.

Latest Patents

Oto's latest patents include a "Condensed plasmid-liposome complex for transfection." This patent describes a plasmid-liposome composition designed for the transfection of cells. The composition consists of plasmid molecules condensed with a polycationic condensing agent and cationic liposomes. Additionally, he has developed an improvement in the method of preparing plasmid-liposome complexes for in vivo transfection. This improvement involves selecting a condensing agent to condense the plasmid before it contacts the liposomes, choosing a working medium, and determining the optimal ratio of liposome lipid to plasmid. The resulting DNA plasmid-liposome complexes formed by this method are also disclosed in his patent.

Career Highlights

Oto is currently associated with Sequus Pharmaceuticals, Inc., where he continues to innovate in the field of biotechnology. His work has the potential to enhance the effectiveness of gene therapy and other medical applications.

Collaborations

Some of his notable coworkers include Shi Kun Huang and Mohammad Hassanipour, who contribute to the collaborative efforts in their research and development projects.

Conclusion

Edwin Kiyoshi Oto's contributions to plasmid-liposome technology are significant and impactful. His innovative patents and ongoing work at Sequus Pharmaceuticals, Inc. highlight his role as a key figure in advancing biotechnology.