The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 22, 1998
Filed:
Mar. 28, 1997
Applicant:
Inventors:
Shi Kun Huang, Castro Valley, CA (US);
Edwin Kiyoshi Oto, Redwood City, CA (US);
Mohammad Hassanipour, Vallejo, CA (US);
Bei Jin, Union City, CA (US);
Assignee:
Sequus Pharmaceuticals, Inc., Menlo Park, CA (US);
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C12N / ; A01N / ; B01J / ; C12P / ;
U.S. Cl.
CPC ...
4353201 ; 424417 ; 424420 ; 4272133 ; 435 691 ;
Abstract
An improvement in a method of preparing plasmid-liposome complexes for in vivo transfection is described. The improvement includes selecting a condensing agent to condense the plasmid prior to contact with the liposomes, selecting a working medium and selecting a ratio of liposome lipid to plasmid. Also disclosed are DNA plasmid-liposome complexes formed by the method.