Dublin, CA, United States of America

Edwin A Saada

USPTO Granted Patents = 4 

Average Co-Inventor Count = 4.8

ph-index = 1


Company Filing History:


Years Active: 2021-2024

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4 patents (USPTO):Explore Patents

Title: Edwin A. Saada: Innovator in CRISPR and Antiviral Research

Introduction

Edwin A. Saada is a prominent inventor based in Dublin, California, known for his significant contributions to the fields of CRISPR technology and antiviral research. With a total of 4 patents, Saada has made strides in developing innovative solutions that address critical challenges in genetic engineering and viral infections.

Latest Patents

Saada's latest patents include groundbreaking work on peptide inhibitors of CRISPR-Cas9. These patents disclose specific and broad-spectrum inhibitory peptides targeting various CRISPR Cas9 variants, including SpyCas9, SauCas9, and CjeCas9. The patents also describe methods for making and using these peptides therapeutically, either to enhance desired targeting or to counteract harmful CRISPR Cas9 components already active in patients. Additionally, Saada has developed small molecule inhibitors for the treatment of alpha viruses. His research involved designing an in vitro assay to measure the activity of the alphavirus non-structural protein 2 (nsP2), which is essential for viral replication. This work led to high-throughput screening of 40,000 small molecules, resulting in the identification of several compounds with promising antiviral efficacy against various viruses, including Chikungunya and Zika.

Career Highlights

Edwin A. Saada is currently employed at National Technology & Engineering Solutions of Sandia, LLC, where he continues to push the boundaries of scientific research. His work has not only advanced the understanding of CRISPR technology but has also provided valuable insights into antiviral drug development.

Collaborations

Throughout his career, Saada has collaborated with notable colleagues, including Joseph S. Schoeniger and Oscar Negrete. These collaborations have further enriched his research and contributed to the success of his innovative projects.

Conclusion

Edwin A. Saada's contributions to the fields of CRISPR technology and antiviral research exemplify the impact of innovation in addressing global health challenges. His work continues to inspire future advancements in these critical areas.

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