Indianapolis, IN, United States of America

Edward Marion Johnstone


Average Co-Inventor Count = 5.2

ph-index = 2

Forward Citations = 27(Granted Patents)


Company Filing History:


Years Active: 1998-2006

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4 patents (USPTO):Explore Patents

Title: The Innovations of Edward Marion Johnstone

Introduction

Edward Marion Johnstone is a notable inventor based in Indianapolis, IN (US). He has made significant contributions to the field of biomedical research, particularly in the study of neurological diseases. With a total of four patents to his name, Johnstone's work focuses on innovative solutions for complex health issues.

Latest Patents

One of Johnstone's latest patents involves a novel β-secretase and the modulation of β-secretase activity. This invention concerns a method of partially purifying this novel β-secretase and its application in assays to screen for potential drug candidates against Alzheimer's disease and other neurological conditions. The novel β-secretase has an estimated molecular weight of about 32-39 kDa or 22-26 kDa in HEK293 cell membrane extracts and human brain samples, respectively. This was calculated from radiation inactivation analysis, and it has a pH optimum at about pH 6.5-7.0.

Career Highlights

Throughout his career, Johnstone has worked with prominent companies such as Eli Lilly and Company and Scios Inc. His experience in these organizations has allowed him to develop and refine his innovative ideas, contributing to advancements in medical research and drug development.

Collaborations

Johnstone has collaborated with several professionals in his field, including Sheila P. Little and Eric P. Dixon. These partnerships have facilitated the exchange of ideas and expertise, further enhancing the impact of his work.

Conclusion

Edward Marion Johnstone's contributions to the field of biomedical research, particularly through his patents related to β-secretase, highlight his innovative spirit and dedication to addressing critical health challenges. His work continues to inspire advancements in the fight against neurological diseases.

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