Edward L Sheldon, Iii

Title: Edward L Sheldon, III: Innovator in Nucleic Acid Labeling Technologies

Introduction

Edward L Sheldon, III is a notable inventor based in Oakland, CA. He has made significant contributions to the field of molecular biology, particularly in the area of nucleic acid labeling. With a total of 3 patents to his name, Sheldon has developed innovative processes that enhance the detection of nucleic acid sequences.

Latest Patents

One of his latest patents is titled "Process for labeling single-stranded nucleic acids and hybridization." This invention involves labeling nucleic acids by complexing an alkylating moiety of a labeling reagent into a single-stranded nucleic acid. The process activates the complex to facilitate covalent bonding between the reagent and the nucleic acid. The labeled nucleic acid serves as a hybridization probe for detecting specific nucleic acid sequences, with a preference for non-radioactive labeling moieties.

Another significant patent is "Process for labeling nucleic acids and hybridization probes." This method allows for the labeling of nucleic acids by intercalating an alkylating intercalation moiety into a partially double-stranded nucleic acid. Similar to his previous patent, this process also aims to create a hybridization probe for detecting nucleic acid sequences, emphasizing the use of non-radioactive labeling reagents.

Career Highlights

Edward L Sheldon, III has been associated with Cetus Corporation, where he has applied his expertise in molecular biology to advance research and development. His work has contributed to the understanding and manipulation of nucleic acids, which is crucial for various applications in biotechnology and medicine.

Collaborations

Throughout his career, Sheldon has collaborated with notable colleagues, including Corey H Levenson and Kary B Mullis. These collaborations have likely fostered an environment of innovation and creativity, leading to advancements in their respective fields.

Conclusion

Edward L Sheldon, III is a distinguished inventor whose work in nucleic acid labeling technologies has made a significant impact in molecular biology. His patents reflect a commitment to advancing scientific knowledge and improving detection methods in genetic research.