Tenafly, NJ, United States of America

Edward James Salaski


Average Co-Inventor Count = 4.5

ph-index = 1

Forward Citations = 2(Granted Patents)


Company Filing History:


Years Active: 2003-2004

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3 patents (USPTO):Explore Patents

Title: Edward James Salaski: Innovator in Cancer Therapeutics

Introduction

Edward James Salaski is an accomplished inventor based in Tenafly, NJ, USA, known for his significant contributions to cancer therapeutics. With three patents to his name, Salaski has focused on developing innovative compounds that could enhance cancer treatment efficacy, particularly for tumors driven by ras oncogenes.

Latest Patents

Salaski's latest patents include the following:

1. **5-(arylsulfonyl)-, 5-(arylsulfinyl), and 5-(arylsulfanyl)-thiazolidine-2,4-diones**: This invention involves a method using novel compounds that serve as inhibitors of farnesyl-protein transferase (FPTase). These compounds may provide an alternative or complementary approach to traditional cancer therapies for treating ras-oncogene-dependent tumors, including pancreatic, colon, bladder, and thyroid cancers.

2. **5-(Substituted)-5-(substituted sulfonyl or sulfanyl) thiazolidine-2,4-diones**: This patent centers around pharmaceutical compositions that inhibit the Ras farnesyl-protein transferase enzyme. As with his other patent, these compounds may also be utilized as alternatives or in conjunction with conventional cancer treatments for the management of ras oncogene-dependent tumors.

Career Highlights

Edward James Salaski is associated with Wyeth Holdings Corporation, a leading company in the pharmaceutical industry. His work has contributed to advancing the understanding and treatment of complex cancers, showcasing his commitment to medical innovation and research.

Collaborations

Throughout his career, Salaski has collaborated with notable colleagues such as Joseph William Epstein and Semiramis Ayral-Kaloustian. These partnerships reflect a collaborative spirit aimed at overcoming the challenges faced in cancer therapeutics.

Conclusion

Edward James Salaski's innovative work in developing thiazolidine-2,4-dione compounds underscores his role as a significant contributor to the field of biotechnology and cancer treatment. His patents reflect a dedication to finding new solutions for patients suffering from challenging cancers, making a lasting impact in the pharmaceutical industry's quest for effective cancer therapies.

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