The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 12, 2003
Filed:
Aug. 23, 2002
Applicant:
Inventors:
Semiramis Ayral-Kaloustian, Tarrytown, NY (US);
Joseph William Epstein, Monroe, NY (US);
Gary H. Birnberg, Tuxedo Park, NY (US);
Edward James Salaski, Tenafly, NJ (US);
Gloria Jean Macewan, Monroe, NY (US);
Katherine Cheung, Paramus, NJ (US);
Assignee:
Wyeth Holdings Corporation, Madison, NJ (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 3/1425 ;
U.S. Cl.
CPC ...
A61K 3/1425 ;
Abstract
This invention relates to a method of using novel 5-(arylsulfonyl)-5-(arylsulfinyl)- and 5-(arylsulfanyl)thiazolidine-2,4-diones of Formula (I), wherein Ar, Ar′, R , m and n are as defined in the specification as inhibitors of Ras FPTase, and may be used as an alternative to, or in conjunction with, traditional cancer therapy for treating ras- oncogene-dependent tumors, such as cancers of the pancreas, colon, bladder, and thyroid