Edward J Ginns

Title: Edward J Ginns: Innovator in Glycosylated Enzyme Therapies

Introduction

Edward J Ginns is a notable inventor based in Bethesda, MD (US), recognized for his contributions to the field of pharmaceutical compositions and enzyme therapies. He holds a total of 3 patents, showcasing his innovative approach to treating genetic disorders such as Gaucher's disease.

Latest Patents

Ginns' latest patents include significant advancements in the treatment of Gaucher's disease. One of his notable inventions is a pharmaceutical composition comprising a therapeutic amount of a glycosylated recombinantly-produced human glucocerebrosidase protein in a pharmaceutically acceptable carrier. This invention is directed towards a method of treating Gaucher's disease by administering this therapeutic composition to affected subjects. Another important patent involves glycolipid enzyme-polymer conjugates, which contain glucocerebrosidase and non-antigenic polymers like polyethylene glycol. These conjugates are designed to circulate for extended periods and exhibit prolonged activity in vivo, making them particularly useful in treating Gaucher's disease.

Career Highlights

Throughout his career, Ginns has worked with prominent organizations, including the United States of America as represented by the Department of Health and Enzon, Inc. His work has significantly impacted the development of enzyme therapies, particularly in the context of lysosomal storage disorders.

Collaborations

Ginns has collaborated with esteemed colleagues such as Brian M Martin and Robert G Shorr, contributing to the advancement of research in enzyme therapies and their applications in medicine.

Conclusion

Edward J Ginns stands out as an influential inventor in the field of pharmaceutical compositions, particularly for his work on glucocerebrosidase therapies. His innovative patents and collaborations have paved the way for improved treatments for Gaucher's disease, highlighting his significant contributions to medical science.