Location History:
- Mesa, AZ (US) (2005)
- Scottsdale, AZ (US) (1991 - 2006)
Company Filing History:
4 out of 2,020 
1 out of 366 
Years Active: 1991-2006
Title: Edward B. Skibo: Innovator in Cancer Treatment
Introduction
Edward B. Skibo is a notable inventor based in Scottsdale, AZ (US). He has made significant contributions to the field of cancer treatment through his innovative research and development of new compounds. With a total of 5 patents, Skibo's work focuses on the treatment of neoplasms and the development of cytotoxic agents.
Latest Patents
Skibo's latest patents include groundbreaking work on the treatment of neoplasms with yujungamycins. Yungamycin A has demonstrated unexpected in vivo anticancer activity. Additionally, new compounds Yungamycin B and C have been disclosed, showing specificity for DT-diaphorase and in vivo anticancer activity. Another significant patent involves cytotoxic N-unsubstituted indoles and cyclopent[b]indoles, which are described as DNA-directed reductive alkylating agents. These compounds represent a significant advancement over previous systems, displaying high specificity for the activating enzyme DT-diaphorase and significant in vivo activity against various tumors.
Career Highlights
Throughout his career, Edward B. Skibo has worked with esteemed institutions such as Arizona State University and Research Corporation Technologies, Inc. His research has led to the development of innovative cancer treatments that have the potential to improve patient outcomes.
Collaborations
Skibo has collaborated with notable colleagues, including Imadul Islam and David S. Alberts. These partnerships have contributed to the advancement of his research and the successful development of his patented technologies.
Conclusion
Edward B. Skibo's contributions to cancer treatment through his innovative patents highlight his dedication to advancing medical science. His work continues to pave the way for new therapeutic options in oncology.