Rockville, MD, United States of America

Edward A Berger

USPTO Granted Patents = 9 

 

Average Co-Inventor Count = 3.6

ph-index = 4

Forward Citations = 56(Granted Patents)


Company Filing History:


Years Active: 1993-2019

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9 patents (USPTO):Explore Patents

Title: **Inventor Edward A. Berger: Innovations in Viral Research**

Introduction

Edward A. Berger, based in Rockville, MD, is a notable inventor with a significant impact in the field of viral research, holding a total of 9 patents. His work primarily focuses on groundbreaking methods to combat viral infections, particularly HIV and Hepatitis C.

Latest Patents

Among his latest innovations, Berger has developed a patent involving **Chimeric antigen receptors to control HIV infection**. This invention introduces novel multispecific chimeric antigen receptor (CAR) proteins designed to enhance immune response against HIV. These CARs consist of extracellular domains fused with a transmembrane domain and a cytoplasmic signaling domain, aimed at co-stimulating effector functions in T cells for improved treatment outcomes.

Another significant patent is his work on a **Flavivirus-based system for production of hepatitis C virus (HCV)**. This invention provides a method to produce isolated, replication-competent HCV particles utilizing transformed mammalian cells. It incorporates a subgenomic replicon from a flavivirus, facilitating the study of HCV entry and the production of structural proteins essential for research and therapeutic applications.

Career Highlights

Edward A. Berger has collaborated with prestigious organizations, including the United States government through the Department of Health and Human Services. His contributions to medical research and innovations have been fundamental in advancing treatments for viral diseases and improving public health outcomes.

Collaborations

Throughout his career, Berger has worked alongside esteemed colleagues, such as Bernard Moss and Thomas R. Fuerst. These collaborations have enabled the pooling of expertise and insights, fostering a research environment conducive to significant scientific advancements.

Conclusion

In summary, Edward A. Berger stands out as a pioneer in viral research, with multiple patents that contribute to the global fight against viral infections. His innovative approaches and collaborative spirit play a critical role in transforming the landscape of medical research, ensuring that new therapeutic avenues continue to be explored.

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