The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 27, 1993
Filed:
Jul. 22, 1988
Applicant:
Inventors:
Edward A Berger, Rockville, MD (US);
Bernard Moss, Bethesda, MD (US);
Thomas R Fuerst, Gaithersburg, MD (US);
Ira Pastan, Potomac, MD (US);
David Fitzgerald, Silver Spring, MD (US);
Tamio Mizukami, Bethesda, MD (US);
Vijay K Chaudhary, Rockville, MD (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12N / ;
U.S. Cl.
CPC ...
536 234 ; 435 697 ; 4351723 ; 4353201 ; 43525233 ;
Abstract
A chimeric gene directing the synthesis of hybrid recombinant fusion protein in a suitable expression vector has been constructed. The fusion protein possesses the property of selective cytotoxicity against specific virus-infected cells. A CD4(178)-PE40 hybrid fusion protein has been made for selectively killing HIV-infected cells.