This inventor holds 1 USPTO granted patent and 2 published patent applications and 1 EPO patent. Top assignees: Consejo Nacional De Investigaciones Cientificas Y Tecnicas (Conicet), Fundacion Instituto Leloir. Active years: 2013.
Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile
Company Filing History:
Years Active: 2013
Title: Innovations of Eduardo Gustavo Alfredo Cafferata
Introduction
Eduardo Gustavo Alfredo Cafferata is a notable inventor based in Buenos Aires, Argentina. He has made significant contributions to the field of biotechnology, particularly in the area of gene expression and cancer treatment. His work has implications for the development of novel therapeutic strategies for tumors.
Latest Patents
Cafferata holds a patent for an isolated DNA fragment of the SPARC human promoter and its use for driving the expression of a heterologous gene in tumor cells. This patent describes an isolated DNA sequence corresponding to a region of the SPARC gene human promoter from base pair -513 to base pair +35. This sequence is capable of driving the expression of a heterologous gene of interest, which can be associated with various promoter sequences, such as radiation-responsive, hypoxia-responsive, and free-radical-responsive sequences. The invention also includes constructs and DNA recombinant expression viral vectors that comprise the isolated sequence of the SPARC gene human promoter and at least one heterologous gene operably linked to it. The promoter sequence drives the expression of the heterologous gene in tumor cells. Additionally, the patent provides pharmaceutical compositions and a method for treating tumors.
Career Highlights
Cafferata has worked with prominent research institutions, including the National Scientific and Technical Research Council (CONICET) and the Leloir Institute Foundation. His research has focused on the intersection of molecular biology and cancer therapy, contributing to advancements in the understanding of gene regulation in tumor cells.
Collaborations
Cafferata has collaborated with esteemed colleagues such as Osvaldo Podhajcer and Maria Veronica Lopez. Their joint efforts have furthered research in the field of gene expression and its applications in medicine.
Conclusion
Eduardo Gustavo Alfredo Cafferata's innovative work in biotechnology and his patent on the SPARC human promoter highlight his contributions to cancer research and treatment. His collaborations and career achievements reflect his commitment to advancing scientific knowledge and therapeutic options.
Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile