Company Filing History:
Years Active: 2021-2023
Title: Innovations and Contributions of Inventor E-Ching Ong in Protein Expression Technologies
Introduction: E-Ching Ong is a notable inventor based in Seattle, Washington, recognized for his significant contributions to the field of biotechnology. With a portfolio of five patents, Ong has focused on developing advanced recombinant expression vectors that enhance protein manufacturing processes. His work is vital in various biotechnological applications, influencing research and development in the industry.
Latest Patents: E-Ching Ong’s latest innovations include patents pertaining to "Expression from Transposon-Based Vectors and Uses" and "Inducible Expression from Transposon-Based Vectors and Uses." These patents disclose recombinant expression vectors equipped with a control sequence that merges a modified Cytomegalovirus (mCMV) enhancer with a rat EF-1alpha intron sequence. The vectors are designed for tetracycline-inducible expression and incorporate PiggyBac inverted terminal repeats (ITRs) to enhance genomic integration into host cell chromosomes. Additionally, the patents detail methods for selecting stable production cell lines for manufacturing proteins of interest and describe mammalian host cells containing the inventive recombinant expression vectors.
Career Highlights: Throughout his career, E-Ching Ong has been affiliated with prominent biotechnology companies, such as Just-Evotec Biologics, Inc. and Just-Evotec Biologies, Inc. His work in these organizations has been pivotal in advancing the understanding and application of recombinant technologies. Ong's commitment to innovation has made him a respected figure within the biotechnology community.
Collaborations: In his professional journey, Ong has collaborated with several esteemed colleagues, including Jeffrey T. McGrew and Pauline S. Smidt. These collaborations have allowed for the exchange of knowledge and expertise, enriching the research output and fostering advancements in protein expression technologies.
Conclusion: E-Ching Ong’s contributions to the development of recombinant expression vectors represent a significant milestone in biotechnology. His patents not only provide innovative solutions for protein expression but also pave the way for further advancements in the field. Through collaboration and dedication, Ong continues to influence the future of biotechnological research and application.