Duncan Casson

Title: Duncan Casson: Innovator in Antibody Development

Introduction

Duncan Casson is a notable inventor based in Royston, GB. He has made significant contributions to the field of biotechnology, particularly in the development of antibodies. With a total of 2 patents to his name, Casson has focused on enhancing the stability and efficacy of therapeutic antibodies.

Latest Patents

Casson's latest patents revolve around antibodies against nerve growth factor (NGF) with enhanced in vivo stability. The inventions provide anti-NGF antibodies that contain an IgG4 constant region comprising a stabilizing hinge region mutation. These antibodies exhibit an unexpectedly long serum half-life in cynomolgus monkeys. Additionally, the patents include pharmaceutical compositions comprising the anti-NGF antibodies, nucleic acids encoding the NGF antibodies, host cells for expressing the NGF antibodies, and methods for using the antibodies to treat NGF-related diseases or conditions.

Career Highlights

Throughout his career, Duncan Casson has worked with various organizations, including Abbott Research B.V. His work has significantly impacted the field of antibody research and development, leading to advancements in therapeutic applications.

Collaborations

Casson has collaborated with notable colleagues such as John Powell and Mark Maginn. These partnerships have contributed to the success of his research and innovations in the biotechnology sector.

Conclusion

Duncan Casson is a prominent figure in the field of antibody development, with a focus on enhancing the stability and effectiveness of therapeutic antibodies. His contributions continue to influence advancements in the treatment of NGF-related diseases.